Turmeric for Patients With Basal Joint Arthritis

Study Purpose

The aim of this study is to assess whether the use of a commercially available nutraceutical, turmeric, is an effective option to manage pain and stiffness in patients with basal joint arthritis. To conduct a pilot Randomized Controlled Trial evaluating the impact of turmeric on basal joint arthritis.

Recruitment Criteria

Accepts Healthy Volunteers

Healthy volunteers are participants who do not have a disease or condition, or related conditions or symptoms

Study Type

An interventional clinical study is where participants are assigned to receive one or more interventions (or no intervention) so that researchers can evaluate the effects of the interventions on biomedical or health-related outcomes.

An observational clinical study is where participants identified as belonging to study groups are assessed for biomedical or health outcomes.

Searching Both is inclusive of interventional and observational studies.

Eligible Ages 40 Years and Over
Gender All
More Inclusion & Exclusion Criteria

Inclusion Criteria:

- 40 years of age or older - English fluency and literacy - Seeking care for basal joint pain - Tender over basal joint - Positive distraction rotation test (rotation of the thumb metacarpal base while applying axial traction) - Radiographic evidence of Eaton stage 1 and 2 only

Exclusion Criteria:

- Secondary gains (litigations or worker compensation) procedures that may interfere with patients' motivation for treatment - Inability or unwillingness to participate in a trial study - Rheumatoid Arthritis or other inflammatory disorder diagnoses - Post-traumatic osteoarthritis - Patients on Coumadin/Steroids/NSAIDs/Tylenol - Diabetes Mellitus - Pregnant or lactating women - Basal joint arthritis of Eaton stage 3 - Patients seeking other treatment for their basal joint arthritis (splint, corticosteroid injection, surgery)

Trial Details

Trial ID:

This trial id was obtained from ClinicalTrials.gov, a service of the U.S. National Institutes of Health, providing information on publicly and privately supported clinical studies of human participants with locations in all 50 States and in 196 countries.


Phase 1: Studies that emphasize safety and how the drug is metabolized and excreted in humans.

Phase 2: Studies that gather preliminary data on effectiveness (whether the drug works in people who have a certain disease or condition) and additional safety data.

Phase 3: Studies that gather more information about safety and effectiveness by studying different populations and different dosages and by using the drug in combination with other drugs.

Phase 4: Studies occurring after FDA has approved a drug for marketing, efficacy, or optimal use.

Lead Sponsor

The sponsor is the organization or person who oversees the clinical study and is responsible for analyzing the study data.

Massachusetts General Hospital
Principal Investigator

The person who is responsible for the scientific and technical direction of the entire clinical study.

Neal Chen, MD
Principal Investigator Affiliation Massachusetts General Hospital
Agency Class

Category of organization(s) involved as sponsor (and collaborator) supporting the trial.

Overall Status Recruiting
Countries United States

The disease, disorder, syndrome, illness, or injury that is being studied.

Thumb Osteoarthritis
Arms & Interventions


Experimental: Turmeric

Subjects in this group will receive turmeric (100 mg pastille) 3 times per day for 6 weeks.

Placebo Comparator: Control

Subjects in this group will receive a placebo pill 3 times per day for 6 weeks.


Dietary Supplement: - Turmeric

Subjects will receive turmeric (100 mg pastille) 3 times per day for 6 weeks.

Other: - Placebo

Subjects in the control group will receive a placebo 3 times per day for 6 weeks.

Contact a Trial Team

If you are interested in learning more about this trial, find the trial site nearest to your location and contact the site coordinator via email or phone. We also strongly recommend that you consult with your healthcare provider about the trials that may interest you and refer to our terms of service below.

Massachusetts General Hospital, Boston, Massachusetts




Massachusetts General Hospital

Boston, Massachusetts, 02114

Site Contact

Neal Chen, MD

[email protected]